Publications

Selected References:

Publications in Refereed Journals

K. J. Castor, J. Mancini, J. Fakhoury, N. Weill, R. Kieltyka, P. Englebienne, N. Avakyan, A. Mittermaier, C. Autexier, N. Moitessier, and H. F. Sleiman; "Platinum(II) Phenanthroimidazoles for G-Quadruplex Targeting", ChemMedChem, 2012, 7(1), 85-94.

C. K. McLaughlin, G. D. Hamblin, F. A. Aldaye, H. Yang, H. F. Sleiman; “A Facile, Modular and High Yield Method to Assemble Three-Dimensional DNA Structures”, Chem. Commun., 2011, 47, 8925 - 8927.

H. Yang, P.K. Lo, C.K. McLaughlin, G.D. Hamblin, F.A. Aldaye and H.F. Sleiman, "Self-Assembly of Metal-DNA Triangles and DNA Nanotubes with Synthetic Junctions", Meth. Mol. Biol., 2011, 749, 33-47.

P. K. Lo, F. Altvater, H. F. Sleiman, “Templated Synthesis of DNA Nanotubes with Controlled Predetermined Lengths”, J. Am. Chem. Soc., 2010, 132, 10212-10214.

P. K. Lo, K. Metera, H. F. Sleiman; “Self-Assembly of Three-Dimensional DNA Nanostructures and Potential Biological Applications”, Curr. Opinion in Chemical Biology, invited review, 2010, 14(5), 597-607.

P. Lo, P. Karam, F. Aldaye, C. K. McLaughlin, G. Hamblin, G. Cosa, H. F. Sleiman, “Loading and Selective Release of Cargo in DNA Nanotubes with Longitudinal Variation”,  Nature Chem. 2010, 2, 319-328.
Selected for Faculty of 1000 Biology, research highlights in Chemistry World (Royal Society for Chemistry), Nano Today (Elsevier), Quebec Science, and popular media (Rutherford radio show, Asharq Awsat newspaper and various web science media

Y. Wen, C. K. McLaughlin, P. K. Lo, H. Yang, H. F. Sleiman, “Stable Gold Nanoparticle Conjugation to Internal DNA Positions: Facile Generation of Discrete Gold Nanoparticle-DNA Assemblies”, Bioconj. Chem. 2010, 21, 1413-1416

N. B. Sankaran, A. Rys, R. Nassif, M. K. Nayak, K. Metera, B. Chen, H. S. Bazzi, H. F. Sleiman, “Ring-Opening Metathesis Polymers for Biodetection and Signal Amplification: Synthesis and Self-Assembly”, Macromolecules, 2010, 43, 5530–5537.

H. Yang, K. Metera, H. F. Sleiman, “DNA modified with metal complexes: applications in the construction of higher-order metal-DNA nanostructures”, invited review in Coord. Chem. Rev., special issue on “Molecular Electronics”, 2010, 254, 2403-2415.

K. Carneiro, H. F. Sleiman, “Long-Range Assembly of DNA into Rigid Nanofibers and Highly Ordered Networks Using a Block Copolymer Approach”, J. Am. Chem. Soc. 2009, 132, 679-685

H. Yang, A. Rys, C.K. McLaughlin, H. F. Sleiman, “Templated Ligand Environments for the Selective Incorporation of  Different Metals into DNA”, Angew. Chem. 2009, 48, 9919-9923.
Selected for cover page

H. Yang, C.K. McLaughlin, G. D. Hamblin, F. A. Aldaye, A. Rys, I. Rouiller, H. F. Sleiman; “Metal-Nucleic Acid Cages”, Nature Chemistry, 2009, 1, 390 - 396. 
News and Views Highlight in Nature Chemistry.

F. A. Aldaye, P. K. Lo, P. Karam, C. K. McLaughlin, G. Cosa and H. F. Sleiman, “Modular construction of DNA nanotubes of tunable geometry and single- or double-stranded character”, Nature Nanotechnology, 2009, 4, 349-352.
Click here for press coverage.

P. K. Lo, H. F. Sleiman, “Nucleobase-Templated Polymerization: Copying the Chain Length and Polydispersity of Living Polymers into Conjugated Polymers” J. Am. Chem. Soc., 2009, 131, 4182-4183.
Highlighted in Nature Chemistry (“Conjugated Polymers: Template Trickery”), March 2009 and Synfacts (“Current Synthetic Organic Chemistry”), May 2009.

F. A. Aldaye, A. Palmer, H. F. Sleiman; “Assembling materials with DNA as the Guide”, Science, invited review, 2008, 321, 1795.

R. Kieltyka, P. Englebienne, J. Fakhoury, C. Autexier, N. Moitessier, H. Sleiman, "A Platinum Supramolecular Square as an Effective G-Quadruplex Binder and Telomerase Inhibitor”, J. Am. Chem. Soc., 2008, 130, 10040-10041.

P. K. Lo, H. F. Sleiman, “Synthesis and Molecular Recognition Properties of DNA-Mimetic Conjugated Polymer”,  Macromolecules, 2008, 41, 5590-5603.

H. Yang, H. F. Sleiman, “Templated Synthesis of Highly Stable, Electroactive and Dynamic Metal-DNA Branched Junctions” ,  Angew. Chem., 2008, 47, 2443-2446. (Selected to appear on the front cover of the Journal)

F. Aldaye, H. F. Sleiman, “Modular Generation of Structurally Switchable 3D- DNA Assemblies”, J. Am. Chem. Soc., 2007, 129, 13376-13377.
Highlighted in Nature (“Gene Boxes”), Nature Materials (“Unnatural Life”) and ACS NANO (“Inspiration from Biology”)

R. Kieltyka, J. Fakhoury, N. Moitessier, H. F. Sleiman, “Platinum Phenanthroimidazole Complexes as G-Quadruplex DNA Selective Binders”, Chemistry, a European Journal, 2007, 14, 1145-1154

F. Aldaye, H. F. Sleiman; “Guest-Mediated Access to a Single DNA Nanostructure from a Library of Multiple Assemblies”, J. Am. Chem. Soc., 2007, 129, 10070-10071.

K. Metera, H. F. Sleiman; “Luminescent Vesicles, Tubules, Bowls and Star Micelles from Ruthenium Bipyridine Block Copolymers”, Macromolecules, 2007, 40, 3733-3738.

M. Slim, N. Durisic, P. Grutter, H. F. Sleiman; “DNA-Protein Non-Covalent Crosslinking: Ruthenium Dipyridophenazine Biotin Complex for the Assembly of Proteins and Gold Nanoparticles on DNA Templates”, ChemBioChem, 2007, 8, 804-812

Y. Ishihara, H. S. Bazzi, V. Toader, F. Godin, H. F. Sleiman; “Molecule-Responsive Block Copolymer Micelles”, Chemistry, a European Journal, 2007, 13, 4560-4570

F. Rakotondradany, H. F. Sleiman, M. A. Whitehead, “Theoretical study of self-assembled hydrogen-bonded azodibenzoic acid tapes and rosettes”, J. Mol. Struct. Theochem, 2007, 806, 39-50.

F. Aldaye, H. F. Sleiman; “Sequential Self-Assembly of a DNA Hexagon as a Template for the Organization of Gold Nanoparticles”, Angew. Chem. Int. Ed. Engl., 2006, 45, 2204-2209.
 (Highlighted by the editors as “Hot Paper” and selected to appear on the cover of the Journal.)

Rakotondradany, Felaniaina; Palmer, Alison; Toader, Violeta; Chen, Bingzhi; Whitehead, M. A.; Sleiman, Hanadi F.. Hydrogen-bond self-assembly of DNA-analogues into hexameric rosettes. Chemical Communications, 2005, 43, 5441-5443. link.

B. Chen, H. F. Sleiman*; "Biotin-Terminated Ruthenium Bipyridine ROMP Polymers: Synthesis and Self-Assembly with Streptavidin", Macromolecules, 2005, 38, 1084-1090 (Full paper), pdf

D. Mitra, N. Di Cesare, H. F. Sleiman*; "Self-Assembly of Cyclic Metal-DNA Nanostructures Using Ruthenium Bipyridine Branched Oligonucleotides", Angew. Chem. Int. Ed. Engl., 2004, 43, 5804-5808. (Communication), pdf

B. Chen, H. F. Sleiman*; "Ruthenium Bipyridine-Containing Polymers and Block Copolymers via Ring-Opening Metathesis Polymerization", Macromolecules, 2004, 37, 5866-5872. (Full paper), pdf

Rezvani, H. S. Bazzi, B. Chen, F. Rakotondradany, H. F. Sleiman*; "Ruthenium(II) Dipyridoquinoxaline-Norbornene: Synthesis, Properties, Crystal Structure, and Use as ROMP Monomer", Inorganic Chemistry, 2004, 43, 5112-5119. (Full paper), pdf

H. S. Bazzi, J. Bouffard, H. F. Sleiman*; "Self-Complementary ABC Triblock Copolymers via Ring-Opening Metathesis Polymerization", Macromolecules, 2003, 36, 7899-7902. (Communication), pdf

F. Rakotondradany, M. A. Whitehead, H. F. Sleiman*; "Photoresponsive Supramolecular Systems: Self-Assembly of Azobenzoic Acid Linear Tapes and Cyclic Tetramers", Chemistry, a European Journal, 2003, 9, 4771-4780. (Full paper), pdf

H. S. Bazzi, H. F. Sleiman*; "Adenine-Containing Block Coplymers via Ring-Opening Metathesis Polymerization: Synthesis and Self-Assembly into Rod Morphologies", Macromolecules, 2002, 9617-9620. (Communication), pdf

J. Dalphond, H. Bazzi, K. Kahrim, H. F. Sleiman*; "Synthesis and Self-Assembly of Polymers Containing Dicarboximide Groups by Living Ring-Opening Metathesis Polymerization", Macromolecular Chem. Phys., 2002, 203, 1988-1994. (Full paper), pdf

H. Bazzi, H. F. Sleiman*; "Synthesis and Self Assembly of Conjugated Polymer Precursors Containing Dichlorocarbonate Groups by Living Ring-Opening Metathesis Polymerization", Macromolecules, 2002, 35, 624-629. (Full paper), pdf

I. Vargas-Baca, D. Mitra, H. Zulyniak, J. Banerjee, H. F. Sleiman*; "Solid-Phase Synthesis of Transition Metal-Linked Branched Oligonucleotides", Angew. Chem. Int. Ed. Engl., 2001, 40, 4629-4632. (Communication), pdf

P.N.W. Baxter, H. F. Sleiman, J.-M. Lehn* and K. Rissanen; "Multicomponent Self-Assembly of [3]-Pseudorotaxanes", Angew. Chem. Int. Ed. Engl., 1997, 36, 1294.

H.F. Sleiman, P.N.W. Baxter, J.-M. Lehn* and K. Airola and K. Rissanen; Multicomponent Self-Assembly: The Generation of Rigid-Rack Multimetallic Pseudorotaxanes, Inorg. Chem., 1997, 36, 4734.

H.F. Sleiman, P.N.W. Baxter, J.-M. Lehn* and K. Rissanen; "Self-Assembly of Rigid-Rack Multimetallic Complexes of Rotaxane Type", Chemical Communications, 1995, 715.

B.A. Arndtsen, H.F. Sleiman, L. McElwee-White* and A. Rheingold; "Electrophilic Reactions of Zero-Valent Tungsten Nitrene and Hydrazido Complexes with Phosphines. Synthesis and Structure of cis-(CO)4WP(Ph)2CH2P(Ph)2NNMe2", Organometallics, 1993, 12, 2440.

C.T. Maxey, H.F. Sleiman and L. McElwee-White*; "Metathesis and Diaziridination Reactions of (CO)5W=C(OMe)(p-XC6H4) with cis-Azobenzene. Electronic and Solvent Effects", Journal of the American Chemical Society, 1992, 114, 5153.

B.A. Arndtsen, H.F. Sleiman, A.K. Chang and L. McElwee-White*; "Evidence for Ambiphilic Behavior in (CO)5W=NPh. Conversion of Carbonyl Compounds to N-Phenyl Imines via Metathesis", Journal of the American Chemical Society, 1991, 113, 4871.

H.F. Sleiman, B.A. Arndtsen and L. McElwee-White*; "Direct Observation of the Low-Valent Hydrazido Complex (CO)5W=NNMe2, a Nitrene Analogue of the Heteroatom-Stabilized Fischer Carbenes", Organometallics, 1991, 10, 541.

H.F. Sleiman, S. Mercer and L. McElwee-White*; "Trapping of the Low-Valent Nitrene Complex (CO)5W=NPh with PPh3. Formation of the Phenylnitrene Transfer Product PhN=PPh3", Journal of the American Chemical Society, 1989, 111, 8007.

H.F. Sleiman and L. McElwee-White*; "Photochemical Azo Metathesis by (CO)5W=C(OCH3)(CH3). Isolation of a Zwitterionic Intermediate", Journal of the American Chemical Society, 1988, 110, 8700.

Books and Book Chapters
H. Sleiman, H. Yan, Co-editors, Nanopatterning Materials with DNA, Taylor & Francis (CRC Press), expected 2010.

R. Kieltyka, H. F. Sleiman, “The use of transition metal complexes to target G-quadruplexes”, invited book chapter in the book “G-Quartet DNA”, Methods in Molecular Biology Series, Humana Press, 2009

K. Carneiro, H. F. Sleiman, “Self-Assembly of Nucleic Acids”, invited chapter in the Book Series “Supramolecular Chemistry: From Molecules to Nanomaterials” John Wiley, 2010.

H. Yang, P. K. Lo, C. K. McLaughlin, G. Hamblin, H. F. Sleiman, “Self-Assembly of Metal-DNA Triangles and DNA Nanotubes with Synthetic Junctions”, invited book chapter in “Protocols in DNA Nanotechnology”, Methods in Molecular Biology Series, Humana Press, 2010 (in press)

R. Kieltyka, H. F. Sleiman, “The use of transition metal complexes to target G-quadruplexes”, invited chapter in the book “G-Quartet DNA”, Methods in Molecular Biology Series, Humana Press, 2009, 668, 223-255.

Patents:

Provisional Patent, “Polymeric Systems for Signal Amplification of Biomolecule Detection”, May 2005, No. 60/684,960

Sleiman, Hanadi; Chen, Bingzhi.   “Polymer compositions and uses thereof”   PCT Int. Appl.  (2006),     71pp.  WO  2006130955 (Patents Filed in USA, Canada and Europe, Dec. 2007)

Provisional Patent, “Nucleotide Modular Assemblies and their Use as Delivery Devices”, Oct. 2007